GRAFIX◊ Cryopreserved Placental Membrane shows high closure rates in the management of chronic wounds15
Study overview
- Retrospective, single-center study
- Patients: Treated with at least one application of GRAFIX Membrane within a 2-year period
- 66 patients with a mean age of 71.1 years
- Wound characteristics:
- 75% had failed other advanced treatment modalities
- Mean wound duration: 38 weeks
- Mean wound size: 6.65 cm2
- 67 wounds were analyzed*
- Primary endpoint: Complete wound closure by week 12, confirmed by image analysis
Results
- 76% of all wounds achieved complete closure by week 12
- 85.2% of DFUs closed
- 67.6% of VLUs closed
- 83.3% of other wounds closed
- Time to complete wound closure (mean): 5.8 weeks
- Number of GRAFIX Membrane applications (mean): 3.8
- 100% of closed wounds remained closed with a mean follow-up of 20.4 months (n=47)
76% of all wounds achieved complete closure by week 12
100% of closed wounds remained closed
Complete wound closure
Quartile 1: 0.42 cm2 - 1.80 cm2
Quartile 2: 1.81 cm2 - 3.37 cm2
Quartile 3: 3.38 cm2 - 6.56 cm2
Quartile 4: 6.57 cm2 - 59.18 cm2
*34 VLUs, 27 DFUs and 6 other wounds (pressure ulcers, traumatic wounds, postsurgical wounds and non-venous vascular ulcers).